shares of Entasis Therapeutics Holdings Inc (ETTX) on
Entasis Therapeutics Holdings, Inc. operates as a clinical stage biopharmaceutical company. The company is headquartered in Waltham, Massachusetts and currently employs 33 full-time employees. The firm is focused on the discovery, development and commercialization of antibacterial products to treat infections caused by multi-drug resistant Gram-negative bacteria. Its lead product candidate ETX2514 and its other product candidate ETX0282 inhibits bacterial resistance, b-lactamase enzyme. Its pipeline includes ETX2514UL, ETX0282CPDp, Zoliflodacin, and non-beta (b)-lactam inhibitors of the penicillin-binding proteins (NBP) Program. ETX2514SUL is a fixed-dose combination of ETX2514 with sulbactam, as a novel IV antibiotic with broad spectrum b-lactamase coverage. Zoliflodacin as a single dose, oral antibiotic monotherapy. ETX0282CPDP is an oral fixed-dose combination of ETX0282 with cefpodoxime proxetil. The firm is developing a class of antibiotics with its NBP program in which it is designing molecules for optimal activity against the penicillin-binding proteins (PBP) enzymes.